OSS has three on-going projects developing new tools and instruments by integrating NASA developed sensors into larger assemblies. Oceaneering is designing the second generation Trace Gas Analyzer for NASA’s Johnson Space Center. The TGA is a hand-held, battery powered quadrupole mass spectrometer that detects and quantifies trace amounts of hydrazine (all three species), ammonia, hydrogen, and oxygen. EVA astronauts will use it to detect and assess potential leaks in the ISS cooling system. We are also working with the Jet Propulsion Lab (JPL), assisting them in developing the Vehicle Cabin Atmosphere Monitor (VCAM), and the Electronic Nose, or ENose, for testing on the International Space Station. The VCAM may become part of the space station’s installed crew healthcare system, where it would be used to identify and quantify concentrations of trace organic compounds in the space station’s air. The ENose is a small, re-locatable instrument that uses an array of chemical sensors to detect changes in the space station’s air composition. Both instruments are being developed and tested on the space station as part of NASA’s new space exploration program and are potentially applicable to commercial uses.